Endocrine Abstracts

Background: Many patients with Addison’s disease experience decreased general wellbeing, mood and physical activity. This decrease in Quality of Life (QoL) is probably related to suboptimal glucocorticoid replacement therapy (GRT). Overreplacement frequently occurs and this can lead to side effects on the long term. The objective of this study was to investigate the effect on QoL of individual adjustment of GRT in order to approach normal cortisol levels as closely as pos...